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The researchers tracked the movement of the protein

The paper relies heavily on time-lapse movies to visualize these cellular dynamics. For example, Video 2 (referenced as part of eLife 16748) shows the accumulation and eventual egress of YFP- -catenin in cells treated with Wnt3a. 16748mp4

The team used HEK293 cells and techniques like fluorescence recovery after photobleaching (FRAP) to measure how fast proteins move within the cell. Where to Find the Paper and Videos Full Text (HTML/PDF): Available at eLife Sciences. The researchers tracked the movement of the protein

-catenin levels rise steadily after activation, the actual transcription of the target gene ( CCND1 ) occurs in "bursts" rather than a constant stream. 16748mp4