It is resistant to extreme temperatures, making it possible to sterilise toys by boiling them for 3–5 minutes or placing them on the top rack of a dishwasher.

Medical-grade silicone is inert, meaning it is unlikely to cause allergic reactions or skin irritation.

Unlike porous materials like "jelly rubber," PVC, or vinyl, high-quality silicone does not have microscopic pores that can trap bacteria or mold.

The market contains many products falsely labelled as silicone. Buyers can use these methods to verify quality: