Over 85% of cases are caused by a specific chromosomal translocation, , which creates the fusion gene.
Ewing sarcoma is a rare and aggressive type of cancer that primarily affects the bone or the surrounding soft tissue. It is most common in children, adolescents, and young adults, typically occurring between the ages of 10 and 20. Overview of Ewing Sarcoma
Most often found in the pelvis, legs (femur), and chest wall.
It belongs to the "small round blue cell tumor" family.