: High concentrations are found in natural sources like tart cherry juice .
: Melatonin modulates both innate and adaptive immunity, specifically reducing excessive innate immune responses through negative regulatory functions. melatonin-goldberg-rar
: While generally safe for short-term use (1–2 months), long-term chronic use has been linked in some research to an increased risk of heart failure . Regulatory & Nutritional Context : High concentrations are found in natural sources