Postbiotic RS5, derived from Lactiplantibacillus plantarum RS5, has emerged as a promising alternative to antibiotics in livestock feed due to its significant antimicrobial activity. To make this functional supplement commercially viable, research has focused on optimizing the production medium to maximize output while minimizing costs. The Optimization Study
This optimized medium enhanced the antimicrobial activity of postbiotic RS5 by 108% compared to standard methods, achieving a potency of
Optimizing Postbiotic RS5 Production: Cost-Effective Solutions for Livestock Introduction
The new medium reduced the production cost by 85% compared to the conventional de Man, Rogosa and Sharpe (MRS) medium.
The researchers successfully developed a refined, low-cost medium that significantly boosted the production and activity of postbiotic RS5.
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The best results were achieved with a medium containing: of glucose (carbon source) of yeast extract (nitrogen source) of sodium acetate of Tween 80 of manganese sulphate